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Cryotherapy eliminates warts by freezing them with a very cold substance, usually liquid nitrogen. Icy crystals form inside the skin cells and as they multiply, they push through cell walls, destroying the live tissue. Freezing the wart kills the skin cells so they cannot continue to spread. With cryotherapy, it is possible to destroy both the wart and the virus that causes it to grow.

For enlarged warts or multiple warts, a series of treatments is necessary.